Tyrosinemia type 1 (HT-1) is a very rare hereditary disorder. People with HT-1 lack the proper enzymes needed to break down tyrosine, an amino acid. This deficiency leads to a toxic buildup of tyrosine in the body which can damage tissue and organs.Learn More
Two important factors are diet and medication.Read More
Discover resources for managing HT-1.Read More
Want to be alerted when new information is available? Sign up now.
ORFADIN is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase indicated for use as an adjunct to dietary restriction of tyrosine and phenylalanine in the treatment of hereditary tyrosinemia type 1 (HT-1).